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T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation †

Since the first description of nuclear autoantigens in the late 1960s and early 1970s, researchers, including ourselves, have found it difficult to establish monoclonal antibodies (mabs) against nuclear antigens, including the La/SS-B (Sjögrens’ syndrome associated antigen B) autoantigen. To date, o...

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Detalles Bibliográficos
Autores principales: Bachmann, Michael P., Bartsch, Tabea, Bippes, Claudia C., Bachmann, Dominik, Puentes-Cala, Edinson, Bachmann, Jennifer, Bartsch, Holger, Arndt, Claudia, Koristka, Stefanie, Loureiro, Liliana R., Kegler, Alexandra, Laube, Markus, Gross, Joanne K., Gross, Tim, Kurien, Biji T., Scofield, R. Hal, Farris, A. Darise, James, Judith A., Schmitz, Marc, Feldmann, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865296/
https://www.ncbi.nlm.nih.gov/pubmed/33530489
http://dx.doi.org/10.3390/ijms22031198