Pseudopeptide Amyloid Aggregation Inhibitors: In Silico, Single Molecule and Cell Viability Studies

Neurodegeneration in Alzheimer’s disease (AD) is defined by pathology featuring amyloid-β (Aβ) deposition in the brain. Aβ monomers themselves are generally considered to be nontoxic, but misfold into β-sheets and aggregate to form neurotoxic oligomers. One suggested strategy to treat AD is to preve...

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Detalles Bibliográficos
Autores principales: Robinson, Morgan, Lou, Jennifer, Mehrazma, Banafsheh, Rauk, Arvi, Beazely, Michael, Leonenko, Zoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865305/
https://www.ncbi.nlm.nih.gov/pubmed/33494369
http://dx.doi.org/10.3390/ijms22031051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865305/
https://www.ncbi.nlm.nih.gov/pubmed/33494369
http://dx.doi.org/10.3390/ijms22031051

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