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Pseudopeptide Amyloid Aggregation Inhibitors: In Silico, Single Molecule and Cell Viability Studies

Neurodegeneration in Alzheimer’s disease (AD) is defined by pathology featuring amyloid-β (Aβ) deposition in the brain. Aβ monomers themselves are generally considered to be nontoxic, but misfold into β-sheets and aggregate to form neurotoxic oligomers. One suggested strategy to treat AD is to preve...

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Detalles Bibliográficos
Autores principales:	Robinson, Morgan, Lou, Jennifer, Mehrazma, Banafsheh, Rauk, Arvi, Beazely, Michael, Leonenko, Zoya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865305/ https://www.ncbi.nlm.nih.gov/pubmed/33494369 http://dx.doi.org/10.3390/ijms22031051

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