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The Relevance of the SH2 Domain for c-Src Functionality in Triple-Negative Breast Cancer Cells

SIMPLE SUMMARY: Triple-Negative breast cancers (TNBC) have not specific therapeutic targets and are considered the most aggressive mammary tumors. c-Src controls several cellular processes: proliferation, differentiation, survival, motility, and angiogenesis. Alteration of c-Src functionality, by in...

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Detalles Bibliográficos
Autores principales: Mayoral-Varo, Víctor, Sánchez-Bailón, María Pilar, Calcabrini, Annarica, García-Hernández, Marta, Frezza, Valerio, Martín, María Elena, González, Víctor M., Martín-Pérez, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865352/
https://www.ncbi.nlm.nih.gov/pubmed/33530373
http://dx.doi.org/10.3390/cancers13030462