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Synthesis of Novel Tryptamine Derivatives and Their Biological Activity as Antitumor Agents

We synthesized five novel tryptamine derivatives characterized by the presence of an azelayl chain or of a 1,1,1-trichloroethyl group, in turn connected to another heterocyclic scaffold. The combination of tryptamin-, 1,1,1-trichloroethyl- and 2-aminopyrimidinyl- moieties produced compound 9 identif...

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Detalles Bibliográficos
Autores principales: Simonetti, Giorgia, Boga, Carla, Durante, Joseph, Micheletti, Gabriele, Telese, Dario, Caruana, Paolo, Ghelli Luserna di Rorà, Andrea, Mantellini, Fabio, Bruno, Samantha, Martinelli, Giovanni, Calonghi, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865355/
https://www.ncbi.nlm.nih.gov/pubmed/33525621
http://dx.doi.org/10.3390/molecules26030683