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Synergism of AZD6738, an ATR Inhibitor, in Combination with Belotecan, a Camptothecin Analogue, in Chemotherapy-Resistant Ovarian Cancer

Epithelial ovarian cancer remains the leading cause of mortality among all gynecologic malignancies owing to recurrence and ultimate development of chemotherapy resistance in the majority of patients. In the chemotherapy-resistant ovarian cancer preclinical model, we investigated whether AZD6738 (an...

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Detalles Bibliográficos
Autores principales: Hur, Jin, Ghosh, Mithun, Kim, Tae Heon, Park, Nahee, Pandey, Kamal, Cho, Young Bin, Hong, Sa Deok, Katuwal, Nar Bahadur, Kang, Minsil, An, Hee Jung, Moon, Yong Wha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865398/
https://www.ncbi.nlm.nih.gov/pubmed/33513721
http://dx.doi.org/10.3390/ijms22031223