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Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy

Tauopathies are a group of more than twenty known disorders that involve progressive neurodegeneration, cognitive decline and pathological tau accumulation. Current therapeutic strategies provide only limited, late-stage symptomatic treatment. This is partly due to lack of understanding of the molec...

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Detalles Bibliográficos
Autores principales: Koren, Shon A., Hamm, Matthew J., Cloyd, Ryan, Fontaine, Sarah N., Chishti, Emad, Lanzillotta, Chiara, Rodriguez-Rivera, Jennifer, Ingram, Alexandria, Bell, Michelle, Galvis-Escobar, Sara M., Zulia, Nicholas, Di Domenico, Fabio, Duong, Duc, Seyfried, Nicholas T., Powell, David, Vandsburger, Moriel, Frolinger, Tal, Hartz, Anika M. S., Koren, John, Axten, Jeffrey M., Laping, Nicholas J., Abisambra, Jose F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865413/
https://www.ncbi.nlm.nih.gov/pubmed/33530349
http://dx.doi.org/10.3390/ijms22031186