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Specific Inhibition of HIF Activity: Can Peptides Lead the Way?

SIMPLE SUMMARY: Cancer cells in solid tumors often experience lack of oxygen (hypoxia), which they overcome with the help of hypoxia inducible transcription factors (HIFs). When HIFs are activated, they stimulate the expression of many genes and cause the production of proteins that help cancer cell...

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Detalles Bibliográficos
Autores principales: Mylonis, Ilias, Chachami, Georgia, Simos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865418/
https://www.ncbi.nlm.nih.gov/pubmed/33499237
http://dx.doi.org/10.3390/cancers13030410