CYP450 Mediates Reactive Oxygen Species Production in a Mouse Model of β-Thalassemia through an Increase in 20-HETE Activity

Oxidative damage by reactive oxygen species (ROS) is one of the main contributors to cell injury and tissue damage in thalassemia patients. Recent studies suggest that ROS generation in non-transfusion-dependent (NTDT) patients occurs as a result of iron overload. Among the different sources of ROS,...

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Detalles Bibliográficos
Autores principales: Bou-Fakhredin, Rayan, Dia, Batoul, Ghadieh, Hilda E., Rivella, Stefano, Cappellini, Maria Domenica, Eid, Assaad A., Taher, Ali T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865490/
https://www.ncbi.nlm.nih.gov/pubmed/33498614
http://dx.doi.org/10.3390/ijms22031106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865490/
https://www.ncbi.nlm.nih.gov/pubmed/33498614
http://dx.doi.org/10.3390/ijms22031106

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