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Lack of Electron Acceptors Contributes to Redox Stress and Growth Arrest in Asparagine-Starved Sarcoma Cells

SIMPLE SUMMARY: Cancer cells require amino acids to grow and survive. Amino acid starvation inhibits cancer growth. This study investigates why the non-essential amino acid asparagine is important for cancer growth by examining metabolite composition in asparagine-deprived sarcoma cells compared to...

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Detalles Bibliográficos
Autores principales: Bauer, Christoph, Quante, Meret, Breunis, Willemijn B., Regina, Carla, Schneider, Michaela, Andrieux, Geoffroy, Gorka, Oliver, Groß, Olaf, Boerries, Melanie, Kammerer, Bernd, Hettmer, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865502/
https://www.ncbi.nlm.nih.gov/pubmed/33499165
http://dx.doi.org/10.3390/cancers13030412