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Pathomechanism Characterization and Potential Therapeutics Identification for Parkinson’s Disease Targeting Neuroinflammation

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the loss of dopaminergic (DAergic) neurons and the presence of α-synuclein-containing Lewy bodies. The unstructured α-synuclein forms insoluble fibrils and aggregates that result in increased reactive oxygen species (RO...

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Detalles Bibliográficos
Autores principales: Chen, Chiung-Mei, Yen, Chien-Yu, Chen, Wan-Ling, Lin, Chih-Hsin, Wu, Yih-Ru, Chang, Kuo-Hsuan, Lee-Chen, Guey-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865530/
https://www.ncbi.nlm.nih.gov/pubmed/33494411
http://dx.doi.org/10.3390/ijms22031062