Cargando…
Pathomechanism Characterization and Potential Therapeutics Identification for Parkinson’s Disease Targeting Neuroinflammation
Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the loss of dopaminergic (DAergic) neurons and the presence of α-synuclein-containing Lewy bodies. The unstructured α-synuclein forms insoluble fibrils and aggregates that result in increased reactive oxygen species (RO...
Autores principales: | Chen, Chiung-Mei, Yen, Chien-Yu, Chen, Wan-Ling, Lin, Chih-Hsin, Wu, Yih-Ru, Chang, Kuo-Hsuan, Lee-Chen, Guey-Jen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865530/ https://www.ncbi.nlm.nih.gov/pubmed/33494411 http://dx.doi.org/10.3390/ijms22031062 |
Ejemplares similares
-
Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation
por: Chiu, Ya-Jen, et al.
Publicado: (2020) -
Lactulose and Melibiose Attenuate MPTP-Induced Parkinson’s Disease in Mice by Inhibition of Oxidative Stress, Reduction of Neuroinflammation and Up-Regulation of Autophagy
por: Lin, Chih-Hsin, et al.
Publicado: (2020) -
Investigating Therapeutic Effects of Indole Derivatives Targeting Inflammation and Oxidative Stress in Neurotoxin-Induced Cell and Mouse Models of Parkinson’s Disease
por: Chiu, Ya-Jen, et al.
Publicado: (2023) -
Biomarker of Neuroinflammation in Parkinson’s Disease
por: Liu, Tsai-Wei, et al.
Publicado: (2022) -
STK39, But Not BST1, HLA-DQB1, and SPPL2B Polymorphism, Is Associated With Han-Chinese Parkinson's Disease in Taiwan
por: Chang, Kuo-Hsuan, et al.
Publicado: (2015)