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Polyhexamethylene Guanidine Phosphate Induces Apoptosis through Endoplasmic Reticulum Stress in Lung Epithelial Cells

Airway epithelial cell death contributes to the pathogenesis of lung fibrosis. Polyhexamethylene guanidine phosphate (PHMG-p), commonly used as a disinfectant, has been shown to be strongly associated with lung fibrosis in epidemiological and toxicological studies. However, the molecular mechanism u...

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Detalles Bibliográficos
Autores principales: Jeong, Mi Ho, Jeon, Mi Seon, Kim, Ga Eun, Kim, Ha Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865558/
https://www.ncbi.nlm.nih.gov/pubmed/33530568
http://dx.doi.org/10.3390/ijms22031215