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Ovulatory Follicular Fluid Facilitates the Full Transformation Process for the Development of High-Grade Serous Carcinoma

SIMPLE SUMMARY: Ovulation is regarded as the culprit of ovarian high-grade serous carcinoma (HGSC). Previously, we discovered IGF2 in the ovulatory follicular fluid (FF), which bathe fallopian tube epithelium (FTE) during ovulation, promotes malignant transformation through the IGF-1R/AKT pathway. T...

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Detalles Bibliográficos
Autores principales: Hsu, Che-Fang, Chen, Pao-Chu, Seenan, Vaishnavi, Ding, Dah-Ching, Chu, Tang-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865564/
https://www.ncbi.nlm.nih.gov/pubmed/33530497
http://dx.doi.org/10.3390/cancers13030468