HIF2alpha-Associated Pseudohypoxia Promotes Radioresistance in Pheochromocytoma: Insights from 3D Models

SIMPLE SUMMARY: Low oxygen levels (hypoxia) as well as genetic defects activating hypoxia signaling pathways (pseudohypoxia) are known to contribute to tumorigenesis and therapy resistance in various cancers. The genetic background of pheochromocytomas and paragangliomas is well characterized and in...

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Detalles Bibliográficos
Autores principales: Seifert, Verena, Richter, Susan, Bechmann, Nicole, Bachmann, Michael, Ziegler, Christian G., Pietzsch, Jens, Ullrich, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865577/
https://www.ncbi.nlm.nih.gov/pubmed/33494435
http://dx.doi.org/10.3390/cancers13030385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865577/
https://www.ncbi.nlm.nih.gov/pubmed/33494435
http://dx.doi.org/10.3390/cancers13030385

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