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HIF2alpha-Associated Pseudohypoxia Promotes Radioresistance in Pheochromocytoma: Insights from 3D Models
SIMPLE SUMMARY: Low oxygen levels (hypoxia) as well as genetic defects activating hypoxia signaling pathways (pseudohypoxia) are known to contribute to tumorigenesis and therapy resistance in various cancers. The genetic background of pheochromocytomas and paragangliomas is well characterized and in...
Autores principales: | Seifert, Verena, Richter, Susan, Bechmann, Nicole, Bachmann, Michael, Ziegler, Christian G., Pietzsch, Jens, Ullrich, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865577/ https://www.ncbi.nlm.nih.gov/pubmed/33494435 http://dx.doi.org/10.3390/cancers13030385 |
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