Multi-Stability and Consequent Phenotypic Plasticity in AMPK-Akt Double Negative Feedback Loop in Cancer Cells

Adaptation and survival of cancer cells to various stress and growth factor conditions is crucial for successful metastasis. A double-negative feedback loop between two serine/threonine kinases AMPK (AMP-activated protein kinase) and Akt can regulate the adaptation of breast cancer cells to matrix-d...

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Detalles Bibliográficos
Autores principales: Chedere, Adithya, Hari, Kishore, Kumar, Saurav, Rangarajan, Annapoorni, Jolly, Mohit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865639/
https://www.ncbi.nlm.nih.gov/pubmed/33530625
http://dx.doi.org/10.3390/jcm10030472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865639/
https://www.ncbi.nlm.nih.gov/pubmed/33530625
http://dx.doi.org/10.3390/jcm10030472

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