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Anticancer Activity of the Acetylenic Derivative of Betulin Phosphate Involves Induction of Necrotic-Like Death in Breast Cancer Cells In Vitro

Betulin (BT) is a natural pentacyclic lupane-type triterpene exhibiting anticancer activity. Betulin derivatives bearing propynoyloxy and phosphate groups were prepared in an effort to improve the availability and efficacy of the drug. In this study, a comparative assessment of the in vitro anticanc...

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Detalles Bibliográficos
Autores principales: Orchel, Arkadiusz, Chodurek, Ewa, Jaworska-Kik, Marzena, Paduszyński, Piotr, Kaps, Anna, Chrobak, Elwira, Bębenek, Ewa, Boryczka, Stanisław, Borkowska, Paulina, Kasperczyk, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865664/
https://www.ncbi.nlm.nih.gov/pubmed/33503929
http://dx.doi.org/10.3390/molecules26030615