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Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice

In Alzheimer’s disease (AD), several studies have reported blood-brain barrier (BBB) breakdown with compromised function. P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are transport proteins localized at the BBB luminal membrane and play an important role in the clearance of amyl...

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Detalles Bibliográficos
Autores principales: Abdallah, Ihab M., Al-Shami, Kamal M., Yang, Euitaek, Kaddoumi, Amal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865722/
https://www.ncbi.nlm.nih.gov/pubmed/33513818
http://dx.doi.org/10.3390/ijms22031231