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A Novel Role for the DNA Repair Enzyme 8-Oxoguanine DNA Glycosylase in Adipogenesis

Cells sustain constant oxidative stress from both exogenous and endogenous sources. When unmitigated by antioxidant defenses, reactive oxygen species damage cellular macromolecules, including DNA. Oxidative lesions in both nuclear and mitochondrial DNA are repaired via the base excision repair (BER)...

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Detalles Bibliográficos
Autores principales: Komakula, Sai Santosh Babu, Blaze, Bhavya, Ye, Hong, Dobrzyn, Agnieszka, Sampath, Harini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865743/
https://www.ncbi.nlm.nih.gov/pubmed/33503804
http://dx.doi.org/10.3390/ijms22031152