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Comparative Evaluation of Novel (177)Lu-Labeled PNA Probes for Affibody-Mediated PNA-Based Pretargeting

SIMPLE SUMMARY: Affibody molecules are small, engineered affinity proteins based on a nonimmunoglobulin scaffold. Affibody-based radionuclide imaging probes have demonstrated excellent tumor targeting. However, the renal clearance of affibody molecules is accompanied by high reabsorption and retenti...

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Detalles Bibliográficos
Autores principales: Tano, Hanna, Oroujeni, Maryam, Vorobyeva, Anzhelika, Westerlund, Kristina, Liu, Yongsheng, Xu, Tianqi, Vasconcelos, Daniel, Orlova, Anna, Karlström, Amelie Eriksson, Tolmachev, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865858/
https://www.ncbi.nlm.nih.gov/pubmed/33525578
http://dx.doi.org/10.3390/cancers13030500