Stereoselective Synthesis of Oxazolidin-2-ones via an Asymmetric Aldol/Curtius Reaction: Concise Total Synthesis of (−)-Cytoxazone

Herein, we are reporting an efficient approach toward the synthesis of 4,5-disubstituted oxazolidin-2-one scaffolds. The developed approach is based on a combination of an asymmetric aldol and a modified Curtius protocol, which uses an effective intramolecular ring closure to rapidly access a range...

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Detalles Bibliográficos
Autores principales: Choi, Hosam, Jang, Hanho, Choi, Joohee, Lee, Kiyoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865922/
https://www.ncbi.nlm.nih.gov/pubmed/33498713
http://dx.doi.org/10.3390/molecules26030597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865922/
https://www.ncbi.nlm.nih.gov/pubmed/33498713
http://dx.doi.org/10.3390/molecules26030597

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