The Role of Panx3 in Age-Associated and Injury-Induced Intervertebral Disc Degeneration

Pannexin 3 (Panx3) is a mechanosensitive, channel-forming glycoprotein implicated in the progression of post-traumatic osteoarthritis. Despite evidence for Panx3 expression in the intervertebral disc (IVD), its function in this cartilaginous joint structure remained unknown. Using Panx3 knockout mic...

Descripción completa

Detalles Bibliográficos
Autores principales: Serjeant, Meaghan, Moon, Paxton M., Quinonez, Diana, Penuela, Silvia, Beier, Frank, Séguin, Cheryle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865929/
https://www.ncbi.nlm.nih.gov/pubmed/33499145
http://dx.doi.org/10.3390/ijms22031080