The Role of Panx3 in Age-Associated and Injury-Induced Intervertebral Disc Degeneration

Pannexin 3 (Panx3) is a mechanosensitive, channel-forming glycoprotein implicated in the progression of post-traumatic osteoarthritis. Despite evidence for Panx3 expression in the intervertebral disc (IVD), its function in this cartilaginous joint structure remained unknown. Using Panx3 knockout mic...

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Detalles Bibliográficos
Autores principales: Serjeant, Meaghan, Moon, Paxton M., Quinonez, Diana, Penuela, Silvia, Beier, Frank, Séguin, Cheryle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865929/
https://www.ncbi.nlm.nih.gov/pubmed/33499145
http://dx.doi.org/10.3390/ijms22031080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865929/
https://www.ncbi.nlm.nih.gov/pubmed/33499145
http://dx.doi.org/10.3390/ijms22031080

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