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The Role of Panx3 in Age-Associated and Injury-Induced Intervertebral Disc Degeneration
Pannexin 3 (Panx3) is a mechanosensitive, channel-forming glycoprotein implicated in the progression of post-traumatic osteoarthritis. Despite evidence for Panx3 expression in the intervertebral disc (IVD), its function in this cartilaginous joint structure remained unknown. Using Panx3 knockout mic...
Autores principales: | Serjeant, Meaghan, Moon, Paxton M., Quinonez, Diana, Penuela, Silvia, Beier, Frank, Séguin, Cheryle A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865929/ https://www.ncbi.nlm.nih.gov/pubmed/33499145 http://dx.doi.org/10.3390/ijms22031080 |
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