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C1q–HA Matrix Regulates the Local Synthesis of Hyaluronan in Malignant Pleural Mesothelioma by Modulating HAS3 Expression

SIMPLE SUMMARY: Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor characterized by poor prognosis due to late diagnosis and the absence of efficient first-line treatments. Hyaluronic acid (HA) and the complement protein C1q represent two pivotal players in the MPM tumor microenviro...

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Detalles Bibliográficos
Autores principales: Vidergar, Romana, Balduit, Andrea, Zacchi, Paola, Agostinis, Chiara, Mangogna, Alessandro, Belmonte, Beatrice, Grandolfo, Micaela, Salton, Francesco, Biolo, Marco, Zanconati, Fabrizio, Confalonieri, Marco, Bulla, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865933/
https://www.ncbi.nlm.nih.gov/pubmed/33499323
http://dx.doi.org/10.3390/cancers13030416