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RUNX3 Transcript Variants Have Distinct Roles in Ovarian Carcinoma and Differently Influence Platinum Sensitivity and Angiogenesis

SIMPLE SUMMARY: Epithelial ovarian cancer treatment is limited by missing predictive markers, frequent chemotherapy resistance and an incomplete understanding of the biology of tumors. Earlier work proved that hypermethylation of the gene RUNX3 coding for a transcription factor has prognostic value,...

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Detalles Bibliográficos
Autores principales: Heinze, Karolin, Hölzer, Martin, Ungelenk, Martin, Gerth, Melanie, Thomale, Jürgen, Heller, Regine, Morden, Claire R., McManus, Kirk J., Mosig, Alexander S., Dürst, Matthias, Runnebaum, Ingo B., Häfner, Norman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866085/
https://www.ncbi.nlm.nih.gov/pubmed/33530588
http://dx.doi.org/10.3390/cancers13030476