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Targeting the Sonic Hedgehog Pathway to Suppress the Expression of the Cancer Stem Cell (CSC)—Related Transcription Factors and CSC-Driven Thyroid Tumor Growth

SIMPLE SUMMARY: Poorly differentiated and anaplastic thyroid cancers respond poorly to surgery, radiation, and hormone therapy. Cancer stem cells play an important role in tumor growth, drug resistance, and recurrence. This study focuses on how the sonic hedgehog (Shh) pathway maintains thyroid canc...

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Detalles Bibliográficos
Autores principales: Lu, Yurong, Zhu, Yiwen, Deng, Shihan, Chen, Yuhuang, Li, Wei, Sun, Jing, Xu, Xiulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866109/
https://www.ncbi.nlm.nih.gov/pubmed/33499351
http://dx.doi.org/10.3390/cancers13030418