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Targeting the Sonic Hedgehog Pathway to Suppress the Expression of the Cancer Stem Cell (CSC)—Related Transcription Factors and CSC-Driven Thyroid Tumor Growth
SIMPLE SUMMARY: Poorly differentiated and anaplastic thyroid cancers respond poorly to surgery, radiation, and hormone therapy. Cancer stem cells play an important role in tumor growth, drug resistance, and recurrence. This study focuses on how the sonic hedgehog (Shh) pathway maintains thyroid canc...
Autores principales: | Lu, Yurong, Zhu, Yiwen, Deng, Shihan, Chen, Yuhuang, Li, Wei, Sun, Jing, Xu, Xiulong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866109/ https://www.ncbi.nlm.nih.gov/pubmed/33499351 http://dx.doi.org/10.3390/cancers13030418 |
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