DNA-Binding Anticancer Drugs: One Target, Two Actions

Amsacrine, an anticancer drug first synthesised in 1970 by Professor Cain and colleagues, showed excellent preclinical activity and underwent clinical trial in 1978 under the auspices of the US National Cancer Institute, showing activity against acute lymphoblastic leukaemia. In 1984, the enzyme DNA...

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Detalles Bibliográficos
Autores principales: Baguley, Bruce C., Drummond, Catherine J., Chen, Ying Yi, Finlay, Graeme J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866126/
https://www.ncbi.nlm.nih.gov/pubmed/33494466
http://dx.doi.org/10.3390/molecules26030552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866126/
https://www.ncbi.nlm.nih.gov/pubmed/33494466
http://dx.doi.org/10.3390/molecules26030552

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