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Differential Role of Threonine and Tyrosine Phosphorylation in the Activation and Activity of the Yeast MAPK Slt2

The Mitogen-Activated Protein Kinase (MAPK) Slt2 is central to signaling through the yeast Cell Wall Integrity (CWI) pathway. MAPKs are regulated by phosphorylation at both the threonine and tyrosine of the conserved TXY motif within the activation loop (T190/Y192 in Slt2). Since phosphorylation at...

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Detalles Bibliográficos
Autores principales: González-Rubio, Gema, Sellers-Moya, Ángela, Martín, Humberto, Molina, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866135/
https://www.ncbi.nlm.nih.gov/pubmed/33498635
http://dx.doi.org/10.3390/ijms22031110