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The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins

In this review, we discuss the major histocompatibility complex (MHC) class II transactivator (CIITA), which is the master regulator of MHC class II gene expression. CIITA is the founding member of the mammalian nucleotide-binding and leucine-rich-repeat (NLR) protein family but stood apart for a lo...

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Detalles Bibliográficos
Autores principales: León Machado, Jorge Alfonso, Steimle, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866136/
https://www.ncbi.nlm.nih.gov/pubmed/33499042
http://dx.doi.org/10.3390/ijms22031074