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Bicyclic Basic Merbarone Analogues as Antiproliferative Agents

Pyrimido-pyrimidine derivatives have been developed as rigid merbarone analogues. In a previous study, these compounds showed potent antiproliferative activity and efficiently inhibited topoisomerase IIα. To further extend the structure–activity relationships on pyrimido-pyrimidines, a novel series...

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Detalles Bibliográficos
Autores principales:	Spallarossa, Andrea, Lusardi, Matteo, Caneva, Chiara, Profumo, Aldo, Rosano, Camillo, Ponassi, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866144/ https://www.ncbi.nlm.nih.gov/pubmed/33494519 http://dx.doi.org/10.3390/molecules26030557

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