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Characterization of Macrophages and Osteoclasts in the Osteosarcoma Tumor Microenvironment at Diagnosis: New Perspective for Osteosarcoma Treatment?

SIMPLE SUMMARY: Due to the great genetic instability of osteosarcoma (OS), a recurrent molecular therapeutic target has not been identified to date. Therefore, characterization of the OS tumor microenvironment (TME) might offer new therapeutic perspectives. The OS2006 trial, originally designed to e...

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Detalles Bibliográficos
Autores principales: Gomez-Brouchet, Anne, Gilhodes, Julia, Acker, Nathalie Van, Brion, Regis, Bouvier, Corinne, Assemat, Pauline, Gaspar, Nathalie, Aubert, Sebastien, Guinebretiere, Jean-Marc, Marie, Beatrice, Larousserie, Frederique, Entz-Werlé, Natacha, de Pinieux, Gonzague, Mascard, Eric, Gouin, Francois, Brousset, Pierre, Tabone, Marie-Dominique, Jimenez, Marta, Le Deley, Marie-Cecile, Blay, Jean-Yves, Brugieres, Laurence, Piperno-Neumann, Sophie, Rédini, Francoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866157/
https://www.ncbi.nlm.nih.gov/pubmed/33498676
http://dx.doi.org/10.3390/cancers13030423