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Neurometals in the Pathogenesis of Prion Diseases

Prion diseases are progressive and transmissive neurodegenerative diseases. The conformational conversion of normal cellular prion protein (PrP(C)) into abnormal pathogenic prion protein (PrP(Sc)) is critical for its infection and pathogenesis. PrP(C) possesses the ability to bind to various neurome...

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Detalles Bibliográficos
Autores principales: Kawahara, Masahiro, Kato-Negishi, Midori, Tanaka, Ken-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866166/
https://www.ncbi.nlm.nih.gov/pubmed/33525334
http://dx.doi.org/10.3390/ijms22031267