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Neurometals in the Pathogenesis of Prion Diseases
Prion diseases are progressive and transmissive neurodegenerative diseases. The conformational conversion of normal cellular prion protein (PrP(C)) into abnormal pathogenic prion protein (PrP(Sc)) is critical for its infection and pathogenesis. PrP(C) possesses the ability to bind to various neurome...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866166/ https://www.ncbi.nlm.nih.gov/pubmed/33525334 http://dx.doi.org/10.3390/ijms22031267 |