Role of Sphingosine 1-Phosphate Signalling Axis in Muscle Atrophy Induced by TNFα in C2C12 Myotubes

Skeletal muscle atrophy is characterized by a decrease in muscle mass causing reduced agility, increased fatigability and higher risk of bone fractures. Inflammatory cytokines, such as tumor necrosis factor-alpha (TNFα), are strong inducers of skeletal muscle atrophy. The bioactive sphingolipid sphi...

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Detalles Bibliográficos
Autores principales: Bernacchioni, Caterina, Ghini, Veronica, Squecco, Roberta, Idrizaj, Eglantina, Garella, Rachele, Puliti, Elisa, Cencetti, Francesca, Bruni, Paola, Donati, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866171/
https://www.ncbi.nlm.nih.gov/pubmed/33525436
http://dx.doi.org/10.3390/ijms22031280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866171/
https://www.ncbi.nlm.nih.gov/pubmed/33525436
http://dx.doi.org/10.3390/ijms22031280

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