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Role of Sphingosine 1-Phosphate Signalling Axis in Muscle Atrophy Induced by TNFα in C2C12 Myotubes
Skeletal muscle atrophy is characterized by a decrease in muscle mass causing reduced agility, increased fatigability and higher risk of bone fractures. Inflammatory cytokines, such as tumor necrosis factor-alpha (TNFα), are strong inducers of skeletal muscle atrophy. The bioactive sphingolipid sphi...
Autores principales: | Bernacchioni, Caterina, Ghini, Veronica, Squecco, Roberta, Idrizaj, Eglantina, Garella, Rachele, Puliti, Elisa, Cencetti, Francesca, Bruni, Paola, Donati, Chiara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866171/ https://www.ncbi.nlm.nih.gov/pubmed/33525436 http://dx.doi.org/10.3390/ijms22031280 |
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