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The Potential of T Cell Factor 1 in Sustaining CD8(+) T Lymphocyte-Directed Anti-Tumor Immunity

SIMPLE SUMMARY: The transcription factor T cell factor 1 (TCF1), encoded by the TCF7 gene, is a key regulator of T-cell fate, which is known to promote T cell proliferation and establish T cell stemness. Importantly, increasing evidence has demonstrated that TCF1 is a critical determinant of the suc...

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Detalles Bibliográficos
Autores principales: Jung, Sungmin, Baek, Jea-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866257/
https://www.ncbi.nlm.nih.gov/pubmed/33572793
http://dx.doi.org/10.3390/cancers13030515