Density Functional Theory-Based Calculation Shed New Light on the Bizarre Addition of Cysteine Thiol to Dopaquinone

Two types of melanin pigments, brown to black eumelanin and yellow to reddish brown pheomelanin, are biosynthesized through a branched reaction, which is associated with the key intermediate dopaquinone (DQ). In the presence of l-cysteine, DQ immediately binds to the –SH group, resulting in the form...

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Detalles Bibliográficos
Autores principales: Kishida, Ryo, Ito, Shosuke, Sugumaran, Manickam, Arevalo, Ryan Lacdao, Nakanishi, Hiroshi, Kasai, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866380/
https://www.ncbi.nlm.nih.gov/pubmed/33573055
http://dx.doi.org/10.3390/ijms22031373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866380/
https://www.ncbi.nlm.nih.gov/pubmed/33573055
http://dx.doi.org/10.3390/ijms22031373

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