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Density Functional Theory-Based Calculation Shed New Light on the Bizarre Addition of Cysteine Thiol to Dopaquinone
Two types of melanin pigments, brown to black eumelanin and yellow to reddish brown pheomelanin, are biosynthesized through a branched reaction, which is associated with the key intermediate dopaquinone (DQ). In the presence of l-cysteine, DQ immediately binds to the –SH group, resulting in the form...
Autores principales: | Kishida, Ryo, Ito, Shosuke, Sugumaran, Manickam, Arevalo, Ryan Lacdao, Nakanishi, Hiroshi, Kasai, Hideaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866380/ https://www.ncbi.nlm.nih.gov/pubmed/33573055 http://dx.doi.org/10.3390/ijms22031373 |
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