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Spermidine Attenuates Oxidative Stress-Induced Apoptosis via Blocking Ca(2+) Overload in Retinal Pigment Epithelial Cells Independently of ROS

Retinal pigment epithelial (RPE) cells occupy the outer layer of the retina and perform various biological functions. Oxidative damage to RPE cells is a major risk factor for retinal degeneration that ultimately leads to vision loss. In this study, we investigated the role of spermidine in a hydroge...

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Detalles Bibliográficos
Autores principales: Kim, Da Hye, Kim, Jeong-Hwan, Hwangbo, Hyun, Kim, So Young, Ji, Seon Yeong, Kim, Min Yeong, Cha, Hee-Jae, Park, Cheol, Hong, Su Hyun, Kim, Gi-Young, Park, Seh-Kwang, Jeong, Ji-Won, Kim, Mi-Young, Choi, Yung Hyun, Lee, Hyesook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866386/
https://www.ncbi.nlm.nih.gov/pubmed/33572992
http://dx.doi.org/10.3390/ijms22031361