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Spermidine Attenuates Oxidative Stress-Induced Apoptosis via Blocking Ca(2+) Overload in Retinal Pigment Epithelial Cells Independently of ROS
Retinal pigment epithelial (RPE) cells occupy the outer layer of the retina and perform various biological functions. Oxidative damage to RPE cells is a major risk factor for retinal degeneration that ultimately leads to vision loss. In this study, we investigated the role of spermidine in a hydroge...
Autores principales: | Kim, Da Hye, Kim, Jeong-Hwan, Hwangbo, Hyun, Kim, So Young, Ji, Seon Yeong, Kim, Min Yeong, Cha, Hee-Jae, Park, Cheol, Hong, Su Hyun, Kim, Gi-Young, Park, Seh-Kwang, Jeong, Ji-Won, Kim, Mi-Young, Choi, Yung Hyun, Lee, Hyesook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866386/ https://www.ncbi.nlm.nih.gov/pubmed/33572992 http://dx.doi.org/10.3390/ijms22031361 |
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