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New 1,2,3-Triazole-Containing Hybrids as Antitumor Candidates: Design, Click Reaction Synthesis, DFT Calculations, and Molecular Docking Study

In an effort to improve and achieve biologically active anticancer agents, a novel series of 1,2,3-triazole-containing hybrids were designed and efficiently synthesized via the Cu-catalyzed azide-alkyne cycloaddition (CuAAC) reaction of substituted-arylazides with alkyne-functionalized pyrazole-[1,2...

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Detalles Bibliográficos
Autores principales: El Azab, Islam H., El-Sheshtawy, Hamdy S., Bakr, Rania B., Elkanzi, Nadia A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866392/
https://www.ncbi.nlm.nih.gov/pubmed/33573040
http://dx.doi.org/10.3390/molecules26030708