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Selumetinib side effects in children treated for plexiform neurofibromas: first case reports of peripheral edema and hair color change

BACKGROUND: Plexiform neurofibromas (PNs) are congenital tumors that affect around 50 % of the subjects with neurofibromatosis type 1. Despite being histologically benign, PNs can grow rapidly, especially in the pediatric age, and cause severe morbidities. In the past, various therapeutic approaches...

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Detalles Bibliográficos
Autores principales: Baldo, Francesco, Magnolato, Andrea, Barbi, Egidio, Bruno, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866429/
https://www.ncbi.nlm.nih.gov/pubmed/33549085
http://dx.doi.org/10.1186/s12887-021-02530-5