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Selumetinib side effects in children treated for plexiform neurofibromas: first case reports of peripheral edema and hair color change
BACKGROUND: Plexiform neurofibromas (PNs) are congenital tumors that affect around 50 % of the subjects with neurofibromatosis type 1. Despite being histologically benign, PNs can grow rapidly, especially in the pediatric age, and cause severe morbidities. In the past, various therapeutic approaches...
Autores principales: | Baldo, Francesco, Magnolato, Andrea, Barbi, Egidio, Bruno, Irene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866429/ https://www.ncbi.nlm.nih.gov/pubmed/33549085 http://dx.doi.org/10.1186/s12887-021-02530-5 |
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