Mesenchymal stem cell-originated exosomal lncRNA HAND2-AS1 impairs rheumatoid arthritis fibroblast-like synoviocyte activation through miR-143-3p/TNFAIP3/NF-κB pathway

BACKGROUND: Long non-coding RNA heart and neural crest derivatives expressed 2-antisense RNA 1 (HAND2-AS1) was found to be elevated in rheumatoid arthritis (RA) fibroblast-like synoviocytes (RA-FLSs). However, whether HAND2-AS1 functions as an exosomal lncRNA related to mesenchymal stem cells (MSCs)...

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Detalles Bibliográficos
Autores principales: Su, Yuhua, Liu, Yajing, Ma, Chao, Guan, Chunxiao, Ma, Xiufen, Meng, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866436/
https://www.ncbi.nlm.nih.gov/pubmed/33549125
http://dx.doi.org/10.1186/s13018-021-02248-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866436/
https://www.ncbi.nlm.nih.gov/pubmed/33549125
http://dx.doi.org/10.1186/s13018-021-02248-1

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