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Non-cell autonomous astrocyte-mediated neuronal toxicity in prion diseases
Under normal conditions, astrocytes perform a number of important physiological functions centered around neuronal support and synapse maintenance. In neurodegenerative diseases including Alzheimer’s, Parkinson’s and prion diseases, astrocytes acquire reactive phenotypes, which are sustained through...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866439/ https://www.ncbi.nlm.nih.gov/pubmed/33546775 http://dx.doi.org/10.1186/s40478-021-01123-8 |