Impairment of Spike-Timing-Dependent Plasticity at Schaffer Collateral-CA1 Synapses in Adult APP/PS1 Mice Depends on Proximity of Aβ Plaques

Alzheimer’s disease (AD) is a multifaceted neurodegenerative disorder characterized by progressive and irreversible cognitive decline, with no disease-modifying therapy until today. Spike timing-dependent plasticity (STDP) is a Hebbian form of synaptic plasticity, and a strong candidate to underlie...

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Detalles Bibliográficos
Autores principales: Garad, Machhindra, Edelmann, Elke, Leßmann, Volkmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866519/
https://www.ncbi.nlm.nih.gov/pubmed/33573114
http://dx.doi.org/10.3390/ijms22031378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866519/
https://www.ncbi.nlm.nih.gov/pubmed/33573114
http://dx.doi.org/10.3390/ijms22031378

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