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USP16 regulates castration-resistant prostate cancer cell proliferation by deubiquitinating and stablizing c-Myc
BACKGROUND: c-Myc, a well-established oncogene, plays an important role in the initiation and progression of various cancers, including prostate cancer. However, its mechanism in cancer cell remains largely unknown and whether there exist a deubiquitinase targeting c-Myc also remains elusive. METHOD...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866668/ https://www.ncbi.nlm.nih.gov/pubmed/33546726 http://dx.doi.org/10.1186/s13046-021-01843-8 |